Carbamazepine -pharmacokinetics,uses,adverse effects

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 CARBAMAZIPINE

  • Its pharmacological action similar to phenytoin
  • Therapeutic effect in mood disorder and has anti diuretic action

USE'S:

  • Trigeminal neuralgia

PHARMCOKINERTICS :

  • ABSORPTON-Oral -slow
  • DISTRIBUTION-75%plasma bound
  • METABOLISM-liver
  • EXCRETION-urine




ADVERSE EFFECTS :

  • Dizziness
  • Sedation
  • Vomiting 
  • Rash

INTERACTION:

  • Decreased efficacy of oral contraceptive 


Important note : Its important to recognize and manage phenytoin induced gum hypertrophy.





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